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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DYNC1LI1 All Species: 28.79
Human Site: S421 Identified Species: 57.58
UniProt: Q9Y6G9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6G9 NP_057225.2 523 56579 S421 S S N V A S V S P I P A G S K
Chimpanzee Pan troglodytes XP_001167584 472 51615 S370 S S N V A S V S P I P A G S K
Rhesus Macaque Macaca mulatta XP_001085468 497 54504 G392 A S E S P A R G P S G S P R T
Dog Lupus familis XP_534236 524 56481 S421 S S N V A S V S P I P A G S K
Cat Felis silvestris
Mouse Mus musculus Q8R1Q8 523 56596 S421 S S N V A S V S P I P A G S K
Rat Rattus norvegicus Q9QXU8 523 56774 S421 S S N V A S V S P I P A G S K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508928 471 51509 S368 S S N V A S V S P I P A G S K
Chicken Gallus gallus Q90828 515 55875 T411 T S N V A S V T P I P A G S K
Frog Xenopus laevis NP_001082059 508 56047 V405 S R S G S T N V A S V S P V P
Zebra Danio Brachydanio rerio NP_001017669 498 54667 T396 P T G R T G P T N V A S V S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395283 470 52288 G368 K Q Q A A L L G V K D P T R S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795494 483 53698 A383 Q E A S P R A A D P R A M R T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.5 60.7 96.3 N.A. 94.6 94.4 N.A. 82.4 86.4 79.7 64.4 N.A. N.A. 45.1 N.A. 47.4
Protein Similarity: 100 88.9 73.8 97.7 N.A. 96.7 96.7 N.A. 85.8 91.7 88.9 76.6 N.A. N.A. 60.7 N.A. 64.4
P-Site Identity: 100 100 13.3 100 N.A. 100 100 N.A. 100 86.6 6.6 6.6 N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: 100 100 33.3 100 N.A. 100 100 N.A. 100 100 33.3 33.3 N.A. N.A. 13.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 9 67 9 9 9 9 0 9 67 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 9 0 9 0 0 0 0 % D
% Glu: 0 9 9 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 9 0 9 0 17 0 0 9 0 59 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0 % I
% Lys: 9 0 0 0 0 0 0 0 0 9 0 0 0 0 59 % K
% Leu: 0 0 0 0 0 9 9 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 0 0 59 0 0 0 9 0 9 0 0 0 0 0 0 % N
% Pro: 9 0 0 0 17 0 9 0 67 9 59 9 17 0 17 % P
% Gln: 9 9 9 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 9 0 9 0 9 9 0 0 0 9 0 0 25 0 % R
% Ser: 59 67 9 17 9 59 0 50 0 17 0 25 0 67 9 % S
% Thr: 9 9 0 0 9 9 0 17 0 0 0 0 9 0 17 % T
% Val: 0 0 0 59 0 0 59 9 9 9 9 0 9 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _